Syphilis of the Aerodigestive Tract

Syphilis, a sexually transmitted infection caused by the Gram-negative bacterium Treponema pallidum , is increasing in prevalence in the United States. It has been our experience that primary and secondary syphilis of the aerodigestive tract can afflict a large age spectrum with varied clinical and histopathologic findings, which can lead to diagnostic problems and frequent misdiagnosis. In this study, we describe the histopathologic patterns of...