Cross the Best with the Best, and Select the Best: HELP in Breeding Selfing Crops

Hybrid‐enabled line profiling (HELP) is a new integrated breeding strategy for self‐fertilizing crops that combines existing and recently identified elements, resulting in a strategy that synergistically exceeds existing breeding concepts. Heterosis in selfing crops is often driven by additive and additive × additive gene action, the molecular basis of which is increasingly being revealed. Unlike nonadditive heterosis, additive forms can be...