Evaluation of renal metabolic response to partial ureteral obstruction with hyperpolarized¹³C MRI

Hyperpolarized 13 C magnetic resonance imaging (MRI) may be used to non‐invasively image the transport and chemical conversion of 13 C–labeled compounds in vivo . In this study, we utilize hyperpolarized 13 C MRI to evaluate metabolic markers in the kidneys longitudinally in a mouse model of partial unilateral ureteral obstruction (pUUO). Partial obstruction was surgically induced in the left ureter of nine adult mice, leaving the right ureter...