Degradation of Androgen Receptor through Small Molecules for Prostate Cancer
Abstract
Prostate cancer is the most common carcinoma among aged males in western countries and more aggressive and lethal castration resistant prostate cancer often occurs after androgen deprivation therapy. The high expression of androgens and androgen receptor is closely related to prostate cancer. Efficient androgen receptor antagonists, such as enzalutamide and ARN-509, could be employed as potent anti-prostate cancer agents. Nevertheless, recent...
Paper Details
Title
Degradation of Androgen Receptor through Small Molecules for Prostate Cancer
Published Date
Jul 31, 2018
Journal
Volume
18
Issue
7
Pages
652 - 667
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