Further Investigations of the Effects of Anti-β₂GP1 Antibodies on Collagen-Induced Platelet Aggregation

Anti-beta-2-glycoprotein 1 (anti-β 2 GP1) antibodies are associated with increased thrombotic risk in patients with autoimmune disease. There is conflicting evidence on the effects of anti-β 2 GP1 antibodies on platelets, with both enhanced and inhibited aggregation previously reported. However, previous studies did not include isotype antibodies to ensure the observed effects were due to anti-β 2 GP1 antibodies. The aims of this study were to...