Strategies and industrial perspectives to improve oral absorption of biological macromolecules

Therapeutic proteins have become a highly attractive drug of choice due to minimal toxicity, high activity and exquisite specificity. Oral delivery of protein drugs is a very interesting area for research, and, naturally, numerous technologies are required to improve the oral bioavailability of therapeutic proteins.This review article systemically generalized the major physiological barriers facing oral macromolecule delivery as well as the...