The In Silico Drug Discovery Toolbox: Applications in Lead Discovery and Optimization
Abstract
Background: Discovery and development of a new drug is a long lasting and expensive journey that takes around 20 years from starting idea to approval and marketing of new medication. Despite R&D expenditures have been constantly increasing in the last few years, the number of new drugs introduced into market has been steadily declining. This is mainly due to preclinical and clinical safety issues, which still represent about 40% of drug...
Paper Details
Title
The In Silico Drug Discovery Toolbox: Applications in Lead Discovery and Optimization
Published Date
Sep 19, 2019
Journal
Volume
26
Issue
21
Pages
3838 - 3873
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