Biotin for the treatment of nail disease: what is the evidence?

Aim: To describe the pharmacology, mechanism of action, and clinical reports using biotin to treat nail conditions.Methods: A review of articles indexed for MEDLINE on PubMed using keywords ‘biotin’ and ‘nail’ was performed and applicable articles were selected for review.Results: Clinical trials have shown an improvement in firmness, hardness, and thickness of brittle nails with oral biotin. There are some case reports and series demonstrating...