A vicious circle between insulin resistance and inflammation in nonalcoholic fatty liver disease
Abstract
Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum of diseases, including simple steatosis, nonalcoholic steatohepatitis (NASH), liver cirrhosis and hepatocellular carcinoma. Lipotoxicity, insulin resistance (IR) and inflammation are involved in the disease process. Lipotoxicity promotes inflammation and IR, which in turn, increase adipocyte lipolysis and exacerbates lipotoxicity. Furthermore, IR and inflammation form a vicious...
Paper Details
Title
A vicious circle between insulin resistance and inflammation in nonalcoholic fatty liver disease
Published Date
Oct 16, 2017
Journal
Volume
16
Issue
1
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