Computational Exploration for Lead Compounds That Can Reverse the Nuclear Morphology in Progeria
Abstract
Progeria is a rare genetic disorder characterized by premature aging that eventually leads to death and is noticed globally. Despite alarming conditions, this disease lacks effective medications; however, the farnesyltransferase inhibitors (FTIs) are a hope in the dark. Therefore, the objective of the present article is to identify new compounds from the databases employing pharmacophore based virtual screening. Utilizing nine training set...
Paper Details
Title
Computational Exploration for Lead Compounds That Can Reverse the Nuclear Morphology in Progeria
Published Date
Jan 1, 2017
Volume
2017
Pages
1 - 15
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