Characterization of mammary-specific disruptions for Tph1 and Lrp5 during murine lactation.
Abstract
Serotonin is a homeostatic regulator of the mammary gland during lactation. The contribution of mammary-derived serotonin to circulating serum serotonin concentrations was previously unknown. We have developed mice with mammary-specific disruptions of tryptophan hydroxylase 1 (Tph1) or low-density lipoprotein receptor-related protein 5 (Lrp5) that are induced during late pregnancy and lactation via use of the whey acidic protein (WAP)-Cre...
Paper Details
Title
Characterization of mammary-specific disruptions for Tph1 and Lrp5 during murine lactation.
Published Date
Nov 9, 2017
Journal
Volume
7
Issue
1
Pages
15155
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Notes
History