Review paper

A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017)

Volume: 27, Issue: 12, Pages: 1341 - 1351
Published: Oct 20, 2017
Abstract
Introduction: Monoacylglycerol lipase is a serine hydrolase that plays a major role in the degradation of the endocannabinoid 2-arachidonoylglycerol. Because of this key role, selective inactivation of MAGL represents an interesting approach to obtain desirable effects in several diseases. Furthermore, MAGL is upregulated in cancer cells and primary tumors and its inhibition in aggressive breast, ovarian, and melanoma cancer cells impairs cell...
Paper Details
Title
A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017)
Published Date
Oct 20, 2017
Volume
27
Issue
12
Pages
1341 - 1351
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