CRISPR is knocking on barn door
Abstract
Genome modification at specific loci in livestock species was only achievable by performing homologous recombination in somatic cells followed by somatic cell nuclear transfer. The difficulty and inefficiency of this method have slowed down the multiple applications of genome modification in farm animals. The discovery of site-specific endonucleases has provided a different and more direct route for targeted mutagenesis, as these enzymes allow...
Paper Details
Title
CRISPR is knocking on barn door
Published Date
Oct 1, 2017
Volume
52
Issue
S4
Pages
39 - 47
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