Systematic investigation into the clonal variability of the non-conventional yeast Pichia pastoris

The non-conventional methylotrophic yeast *Pichia pastoris* has become a firmly established host for recombinant protein production in both the industry and academia. High product titers, an efficient secretory machinery and the ability to express complex proteins from bacterial to human origin have given *P. pastoris* an advantage over many other host systems. In recent years, its aptitude for foreign gene expression has also been applied in a...