P442 Potential for population-level healthcare quality improvement with a new treatment modality for chronic rhinosinusitis

Patient satisfaction is increasingly used to measure healthcare quality. Chronic rhinosinusitis (CRS) is common and often characterized by suboptimal outcomes, notably low satisfaction with current intranasal corticosteroids (INS). OPN-375 uses a new “exhalation delivery system” designed to place steroid high and deep into regions of the nasal cavity that are not well accessed by current INS. There is potential to increase population-level...