Purine and Pyrimidine Phosphoribosyltransferases: A Versatile Tool for Enzymatic Synthesis of Nucleoside-5'-monophosphates

In recent years, enzymatic methods have shown to be an efficient and sustainable alternative for the synthesis of nucleosides and nucleoside-5'-monophosphates (NMPs) to the traditional multistep chemical methods, since chemical glycosylation reactions include several protection-deprotection steps and the use of chemical reagents and organic solvents that are expensive and environmentally harmful.In this mini-review, we want to illustrate the...