Ribosomopathies: There’s strength in numbers
Abstract
Ribosomopathies are a group of human disorders most commonly caused by ribosomal protein haploinsufficiency or defects in ribosome biogenesis. These conditions manifest themselves as physiological defects in specific cell and tissue types. We review current molecular models to explain ribosomopathies and attempt to reconcile the tissue specificity of these disorders with the ubiquitous requirement for ribosomes in all cells. Ribosomopathies as a...
Paper Details
Title
Ribosomopathies: There’s strength in numbers
Published Date
Nov 2, 2017
Journal
Volume
358
Issue
6363
Pages
eaan2755 - eaan2755
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Notes
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