Slug/Pcad pathway controls epithelial cell dynamics in mammary gland and breast carcinoma
Abstract
Mammary gland morphogenesis results from the coordination of proliferation, cohort migration, apoptosis and stem/progenitor cell dynamics. We showed earlier that the transcription repressor Slug is involved in these functions during mammary tubulogenesis. Slug is expressed by a subpopulation of basal epithelial cells, co-expressed with P-cadherin (Pcad). Slug-knockout mammary glands showed excessive branching, similarly to Pcad-knockout. Here,...
Paper Details
Title
Slug/Pcad pathway controls epithelial cell dynamics in mammary gland and breast carcinoma
Published Date
Oct 9, 2017
Journal
Volume
37
Issue
5
Pages
578 - 588
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History