FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling

Volume: 9, Issue: 5, Pages: 1423 - 1431
Published: Nov 14, 2017
Abstract
Summary null Genome editing and human induced pluripotent stem cells hold great promise for the development of isogenic disease models and the correction of disease-associated mutations for isogenic tissue therapy. CRISPR-Cas9 has emerged as a versatile and simple tool for engineering human cells for such purposes. However, the current protocols to derive genome-edited lines require the screening of a great number of clones to obtain one free of...
Paper Details
Title
FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling
Published Date
Nov 14, 2017
Volume
9
Issue
5
Pages
1423 - 1431
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