Budding yeast CENP-ACse4interacts with the N-terminus of Sgo1 and regulates its association with centromeric chromatin
Abstract
Shugoshin is an evolutionarily conserved protein, which is involved in tension sensing on mitotic chromosomes, kinetochore biorientation, and protection of centromeric (CEN) cohesin for faithful chromosome segregation. Interaction of the C-terminus of Sgo1 with phosphorylated histone H2A regulates its association with CEN and pericentromeric (peri-CEN) chromatin, whereas mutations in histone H3 selectively compromise the association of Sgo1 with...
Paper Details
Title
Budding yeast CENP-ACse4interacts with the N-terminus of Sgo1 and regulates its association with centromeric chromatin
Published Date
Jan 2, 2018
Journal
Volume
17
Issue
1
Pages
11 - 23
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