Efficient radiosynthesis of a [18F]-phosphonium salt containing closo-carborane

An efficient synthesis of an 18 F-labelled phosphonium salt containing closo -carborane is described. The preparation of this salt was attempted using both single-step and two-step protocols, with greater success found for the latter. An X-ray structure for the unlabelled 19 F salt is also presented. • An efficient synthesis of an 18 F-labelled phosphonium salt containing closo -carborane is described. • The preparation of the radiolabelled salt...