Mechanisms of P-Glycoprotein Modulation by Semen Strychni Combined with Radix Paeoniae Alba

Volume: 2017, Pages: 1 - 8
Published: Jan 1, 2017
Abstract
Semen Strychni has been extensively used as a Chinese herb, but its therapeutic window is narrowed by the strong toxicity of the compound, which limits its effectiveness. Radix Paeoniae Alba has been reported to reduce the toxic effects and increase the therapeutic effects of Semen Strychni, but the underlying mechanism remains unknown. This research aimed to explore the mechanism through which P-glycoprotein (P-gp) is modulated by Semen...
Paper Details
Title
Mechanisms of P-Glycoprotein Modulation by Semen Strychni Combined with Radix Paeoniae Alba
Published Date
Jan 1, 2017
Volume
2017
Pages
1 - 8
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