Improving the performance of cell biocatalysis and the productivity of acetoin from 2,3-butanediol using a compressed oxygen supply

Acetoin is useful as a food additive and a valuable intermediate chemicalwhich can be made from 2, 3-butanediol. To improve the production of acetoin, a compressed oxygen supply in a sealed aerated stirred tank reactor (COS-SSTR) based method is adopted. The strain of Gluconobacter oxydansNL71 was used for bio-oxidization of 2, 3-butanediol to acetoin. After optimization of the fed-batch concentration in an aerated stirred-tank reactor, the...