Targeted mutagenesis in a human-parasitic nematode
Abstract
Parasitic nematodes infect over 1 billion people worldwide and cause some of the most common neglected tropical diseases. Despite their prevalence, our understanding of the biology of parasitic nematodes has been limited by the lack of tools for genetic intervention. In particular, it has not yet been possible to generate targeted gene disruptions and mutant phenotypes in any parasitic nematode. Here, we report the development of a method for...
Paper Details
Title
Targeted mutagenesis in a human-parasitic nematode
Published Date
Oct 10, 2017
Journal
Volume
13
Issue
10
Pages
e1006675 - e1006675
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