Review paper
Principles of mucin structure: implications for the rational design of cancer vaccines derived from MUC1-glycopeptides
Abstract
Cancer is currently one of the world's most serious public health problems. Significant efforts are being made to develop new strategies that can eradicate tumours selectively without detrimental effects to healthy cells. One promising approach is focused on the design of vaccines that contain partially glycosylated mucins in their formulation. Although some of these vaccines are in clinical trials, a lack of knowledge about the molecular basis...
Paper Details
Title
Principles of mucin structure: implications for the rational design of cancer vaccines derived from MUC1-glycopeptides
Published Date
Jan 1, 2017
Journal
Volume
46
Issue
23
Pages
7154 - 7175
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History