Effect of a series of essential oil molecules on DPPC membrane fluidity: a biophysical study

Monoterpenes (MTs) were known to cause biological membranes perturbation. Here, the interaction of four (eucalyptol, pulegone, terpineol, and thymol) with dipalmitoylphosphatidylcholine (DPPC) liposomes was studied by Raman spectroscopy, differential scanning calorimetry and fluorescence anisotropy. Liposomes were prepared by the thin-film hydration method, and MTs were added to DPPC at various molar percentages (from 0 to 25%). All the studied...