Treatment of Peyronie's Disease with Collagenase Clostridium histolyticum and Vacuum Therapy: A Randomized, Open-Label Pilot Study

Collagenase Clostridium histolyticum (CCH) is indicated for the treatment of penile curvature in adult men with Peyronie's disease (PD) with palpable plaque and curvature deformity of at least 30° at the start of therapy.To evaluate the efficacy and safety of CCH plus vacuum-pump therapy with and without penile modeling for the management of PD.Adult men with PD and penile curvature of at least 30° were randomly assigned to receive CCH 0.58 mg...