Purinergic Signalling: Therapeutic Developments
Abstract
Purinergic signalling, i.e., the role of nucleotides as extracellular signalling molecules, was proposed in 1972. However, this concept was not well accepted until the early 1990's when receptor subtypes for purines and pyrimidines were cloned and characterised, which includes four subtypes of the P1 (adenosine) receptor, seven subtypes of P2X ion channel receptors and 8 subtypes of the P2Y G protein-coupled receptor. Early studies were largely...
Paper Details
Title
Purinergic Signalling: Therapeutic Developments
Published Date
Sep 25, 2017
Journal
Volume
8
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Notes
History