Current Trends and Research Challenges Regarding “Preparation for Oxidative Stress”

Survival under stress, such as exposure to hypoxia, anoxia, freezing, dehydration, air exposure of water breathing organisms and estivation, is commonly associated to enhanced endogenous antioxidants, a phenomenon coined ‘preparation for oxidative stress’ (POS). The regulation of free radical metabolism seems to be crucial under these selective pressures, since this response is widespread among animals. A hypothesis of how POS works at the...