Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis
Abstract
Cystic fibrosis (CF) lung disease is defined by large numbers of neutrophils and associated damaging products in the airway. Delayed neutrophil apoptosis is described in CF although it is unclear whether this is a primary neutrophil defect or a response to chronic inflammation. Increased levels of neutrophil extracellular traps (NETs) have been measured in CF and we aimed to investigate the causal relationship between these phenomena and their...
Paper Details
Title
Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis
Published Date
Sep 15, 2017
Journal
Volume
73
Issue
2
Pages
134 - 144
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