C1q/TNF‐related protein 9 improves the anti‐contractile effects of perivascular adipose tissue via the AMPK‐eNOS pathway in diet‐induced obese mice

Summary The anti‐contractile property of perivascular adipose tissue ( PVAT ) is abolished through an endothelium‐dependent pathway in obesity. C1q/tumor necrosis factor‐related protein ( CTRP )9 improved endothelial function by promoting endothelium‐dependent vasodilatation. The aims of this study were to investigate whether CTRP 9 improves the anti‐contractile effect of PVAT and protects against PVAT dysfunction in obese mice. The mice were...