OR37 Persistence of T cells from the first donor after a second allogeneic stem cell transplantation

The monitoring of chimerism is a standard procedure to help assess engraftment and achievement of full donor lymphoid cells after allogeneic stem cell transplantation. T cell chimerism analysis is essential since T cells support the engraftment of hematopoietic stem cells and progenitor cells. TCRαβ T cells provide anti-tumor activity but can also cause graft vs. host disease (GVHD). In contrast, TCRγδ T cells have been found not to be...