CRISPR: Established Editor of Human Embryos?

Published on Sep 1, 2017in Cell Stem Cell21.46
· DOI :10.1016/j.stem.2017.08.007
Xiao-Jiang Li61
Estimated H-index: 61
(Emory University),
Zhuchi Tu7
Estimated H-index: 7
(JNU: Jinan University)
+ 1 AuthorsLi Shihua76
Estimated H-index: 76
(Emory University)
Off-target effects and mosaicism are major concerns for applying CRISPR-Cas9 to correct genetic mutations. A recent article in Nature by Ma et al. (2017) uses an elegant CRISPR-Cas9 approach that repairs a genetic mutation in human embryos with negligible mosaicism and no off-target effects, bringing this editing tool closer to clinical application.
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  • Citations (1)
#1Hong Ma (Oregon National Primate Research Center)H-Index: 27
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View next paperMosaicism in CRISPR/Cas9-mediated Genome editing.