Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Abstract
Coxsackievirus A6 (CVA6) has recently emerged as a major cause of hand, foot and mouth disease in children worldwide but no vaccine is available against CVA6 infections. Here, we demonstrate the isolation of two forms of stable CVA6 particles-procapsid and A-particle-with excellent biochemical stability and natural antigenicity to serve as vaccine candidates. Despite the presence (in A-particle) or absence (in procapsid) of capsid-RNA...
Paper Details
Title
Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Published Date
Sep 11, 2017
Journal
Volume
8
Issue
1
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