A calpain inhibitor protects against fractalkine production in lipopolysaccharide-treated endothelial cells
Volume: 36, Issue: 3, Pages: 224 - 231
Published: Sep 30, 2017
Abstract
Background Fractalkine (CX3CL1) is a chemokine with a unique CX3C motif and is produced by endothelial cells stimulated with lipopolysaccharide (LPS), tumor necrosis factor (TNF)-α, interleukin (IL)-1, and interferon-γ. There have been several reports that the caspase/calpain system is activated in endotoxemia, which leads to cellular apoptosis and acute inflammatory processes. We aimed to determine the role of the caspase/calpain system in...
Paper Details
Title
A calpain inhibitor protects against fractalkine production in lipopolysaccharide-treated endothelial cells
Published Date
Sep 30, 2017
Volume
36
Issue
3
Pages
224 - 231
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