Identification of a novel single chain fragment variable antibody targeting CD24-expressing cancer cells

Volume: 190, Pages: 240 - 246
Published: Oct 1, 2017
Abstract
CD24 is a heavy glycosylated protein that is overexpressed in numerous cancer and cancer stem cells. It is involved in the development, invasion, and metastasis of the cancer cells. CD24 can be considered in targeted cancer therapy as a new target. Here, phage display technology was used for the identification of novel scFv antibodies against CD24. To do so, the CD24 protein was expressed and purified from a stable transgenic CHO cell line. The...
Paper Details
Title
Identification of a novel single chain fragment variable antibody targeting CD24-expressing cancer cells
Published Date
Oct 1, 2017
Volume
190
Pages
240 - 246
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