Original paper
Lewis Acid Catalyzed Formal [3+2] Cycloaddition of Donor‐Acceptor Cyclopropanes and 1‐Azadienes: Synthesis of Imine Functionalized Cyclopentanes and Pyrrolidine Derivatives
Abstract
Lewis acid catalyzed formal [3+2] cycloadditions of 1‐azadienes with donor acceptor cyclopropanes to synthesize varieties of imine functionalized cyclopentanes and pyrrolidine derivatives in moderate to high yield have been developed. Moreover, pharmaceutically relevant azabicyclo[3.2.1]octane, bearing two all‐carbon quaternary stereogenic centers at the bridgehead positions, has been synthesized by nosyl group deprotection and intramolecular...
Paper Details
Title
Lewis Acid Catalyzed Formal [3+2] Cycloaddition of Donor‐Acceptor Cyclopropanes and 1‐Azadienes: Synthesis of Imine Functionalized Cyclopentanes and Pyrrolidine Derivatives
Published Date
Sep 25, 2017
Volume
359
Issue
21
Pages
3848 - 3854
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