TNFR2: The new Treg switch?
Abstract
Three recent publications identified the TNF/TNR2 pathway as a new target to reduce graft-versus-host-disease through regulatory T cells activation or to potentially switch on a strong anti-leukemic effect through regulatory T cells blockade in allogeneic hematopoietic stem cell transplantation. This identified the TNF/TNR2 pathway as a swith and as a new target for immune checkpoint therapy to modulate the immune regulation in this clinical...
Paper Details
Title
TNFR2: The new Treg switch?
Published Date
Sep 21, 2017
Journal
Volume
7
Issue
1
Pages
e1373236 - e1373236
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Notes
History