The novel 19G endobronchial USS (EBUS) needle samples processed as tissue “core biopsies” facilitate PD-L1 and other biomarker testing in lung cancer specimens: case report and the view point from the Respiratory Physician and the Pathologist

The immunohistochemical expression of Programmed Death Ligand ( PD‐L1 ) predicts responses to PD ‐1/ PD‐L1 inhibitors in non‐small cell lung cancer ( NSCLC ). PD‐L1 testing is currently only recommended on tissue specimens; however, in many patients, cytology samples are the only specimens available. The introduction of the novel 19G “core‐biopsy” needle has revolutionized the utility of endobronchial USS ‐guided biopsy ( EBUS ) by providing...