Neurochemical Aspects of β-Amyloid Cascade Hypothesis for Alzheimer’s Disease

Pages: 1 - 46
Published: Jan 1, 2017
Abstract
Alzheimer's disease (AD) is an age-associated neurodegenerative disorder that causes severe impairment of cognitive function, leading to a drastic decline in the quality of life. Neuropathological features of AD include the accumulation of β-amyloid (Aβ) and deposition of extracellular senile plaques and accumulation of intraneuronal tangles that consist of aggregated and hyperphosphorylated Tau protein. According to the Aβ cascade hypothesis of...
Paper Details
Title
Neurochemical Aspects of β-Amyloid Cascade Hypothesis for Alzheimer’s Disease
Published Date
Jan 1, 2017
Pages
1 - 46
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