Injection of oxytocin into paraventricular nucleus reverses depressive-like behaviors in the postpartum depression rat model
Abstract
Oxytocin (OXT) has been considered as a neuroregulator mediating social behaviors and stress-related disorders. Recent clinical studies suggest that OXT might also act as antidepressant in postpartum depression (PPD) patients, but the mechanism is still unknown. In the present study, we explored the effect of OXT in paraventricular nucleus (PVN) and possible signaling pathway involved in a PPD rat model induced by gestation restraint stress...
Paper Details
Title
Injection of oxytocin into paraventricular nucleus reverses depressive-like behaviors in the postpartum depression rat model
Published Date
Jan 1, 2018
Journal
Volume
336
Pages
236 - 243
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