antioxidant activity

pancreatic lipase

Evidence-based complementary and alternative medicine

Ethanol (95%) and dichloromethane : methanol (DCM : M, 1 : 1 v/v) bark extracts (BEs) and leaf extracts (LEs) of authenticated Ceylon cinnamon (CC) were studied for antiamylase, antiglucosidase, anticholinesterases, and antiglycation and glycation reversing potential in bovine serum albumin- (BSA-) glucose and BSA-methylglyoxal models in vitro . Further, total proanthocyanidins (TP) were quantified. Results showed significant differences (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>p</mml:mi><mml:mo>&lt;</mml:mo><mml:mn fontstyle="italic">0.05</mml:mn></mml:math>) between bark and leaf extracts for the studied biological activities (except antiglucosidase) and TP. BEs showed significantly high (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M2"><mml:mi>p</mml:mi><mml:mo>&lt;</mml:mo><mml:mn fontstyle="italic">0.05</mml:mn></mml:math>) activities for antiamylase (IC 50 : <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M3"><mml:mn fontstyle="italic">214</mml:mn><mml:mo>±</mml:mo><mml:mn fontstyle="italic">2</mml:mn></mml:math>–<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M4"><mml:mn fontstyle="italic">215</mml:mn><mml:mo>±</mml:mo><mml:mn fontstyle="italic">10</mml:mn></mml:math> μ g/mL), antibutyrylcholinesterase (IC 50 : <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M5"><mml:mn fontstyle="italic">26.62</mml:mn><mml:mo>±</mml:mo><mml:mn fontstyle="italic">1.66</mml:mn></mml:math>–<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M6"><mml:mn fontstyle="italic">36.09</mml:mn><mml:mo>±</mml:mo><mml:mn fontstyle="italic">0.83</mml:mn></mml:math> μ g/mL), and glycation reversing in BSA-glucose model (EC 50 : <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M7"><mml:mn fontstyle="italic">94.33</mml:mn><mml:mo>±</mml:mo><mml:mn fontstyle="italic">1.81</mml:mn></mml:math>–<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M8"><mml:mn fontstyle="italic">107.16</mml:mn><mml:mo>±</mml:mo><mml:mn fontstyle="...

Antiamylase, Anticholinesterases, Antiglycation, and Glycation Reversing Potential of Bark and Leaf of Ceylon Cinnamon (Cinnamomum zeylanicum Blume) In Vitro