A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice
Abstract
Calorie restriction, without malnutrition, has been shown to increase lifespan and is associated with a shift away from glycolysis toward beta-oxidation. The objective of this study was to mimic this metabolic shift using low-carbohydrate diets and to determine the influence of these diets on longevity and healthspan in mice. C57BL/6 mice were assigned to a ketogenic, low-carbohydrate, or control diet at 12 months of age and were either allowed...
Paper Details
Title
A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice
Published Date
Sep 1, 2017
Journal
Volume
26
Issue
3
Pages
539 - 546.e5
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