Neutral tumor evolution in myeloma is associated with poor prognosis

David W. Johnson; Oleg Lenive; Jonathan S. Mitchell; Graham Jackson; Roger G. Owen; Mark T. Drayson; Gordon Cook; John R Jones; Charlotte Pawlyn; Faith E. Davies; Richard S. Houlston; Martin Kaiser

doi:https://doi.org/10.1182/blood-2016-11-750612

doi.org/10.1182/blood-2016-11-750612

Neutral tumor evolution in myeloma is associated with poor prognosis

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..., Martin Kaiser

46

Blood20.30

Volume: 130, Issue: 14, Pages: 1639 - 1643

Published: Oct 5, 2017

Abstract

Key Points A significant proportion of MM is dominated by neutral evolutionary dynamics. Neutral MM tumors are characterized by shorter survival, consistent with reduced sensitivity to drugs targeting the MM...

Paper Fields

Paper Details

Title

Neutral tumor evolution in myeloma is associated with poor prognosis

DOI

doi.org/10.1182/blood-2016-11-750612

Published Date

Oct 5, 2017

Journal

Blood

Volume

130

Issue

14

Pages

1639 - 1643

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