Adult-onset obesity is triggered by impaired mitochondrial gene expression
Abstract
Mitochondrial gene expression is essential for energy production; however, an understanding of how it can influence physiology and metabolism is lacking. Several proteins from the pentatricopeptide repeat (PPR) family are essential for the regulation of mitochondrial gene expression, but the functions of the remaining members of this family are poorly understood. We created knockout mice to investigate the role of the PPR domain 1 (PTCD1)...
Paper Details
Title
Adult-onset obesity is triggered by impaired mitochondrial gene expression
Published Date
Aug 4, 2017
Journal
Volume
3
Issue
8
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