Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes
Abstract
The dynamics and regulation of HIV-1 nuclear import and its intranuclear movements after import have not been studied. To elucidate these essential HIV-1 post-entry events, we labeled viral complexes with two fluorescently tagged virion-incorporated proteins (APOBEC3F or integrase), and analyzed the HIV-1 dynamics of nuclear envelope (NE) docking, nuclear import, and intranuclear movements in living cells. We observed that HIV-1 complexes...
Paper Details
Title
Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes
Published Date
Aug 21, 2017
Journal
Volume
13
Issue
8
Pages
e1006570 - e1006570
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