Green fluorescent genetically encoded calcium indicator based on calmodulin/M13-peptide from fungi

Volume: 12, Issue: 8, Pages: e0183757 - e0183757
Published: Aug 24, 2017
Abstract
Currently available genetically encoded calcium indicators (GECIs) utilize calmodulins (CaMs) or troponin C from metazoa such as mammals, birds, and teleosts, as calcium-binding domains. The amino acid sequences of the metazoan calcium-binding domains are highly conserved, which may limit the range of the GECI key parameters and cause undesired interactions with the intracellular environment in mammalian cells. Here we have used fungi,...
Paper Details
Title
Green fluorescent genetically encoded calcium indicator based on calmodulin/M13-peptide from fungi
Published Date
Aug 24, 2017
Journal
Volume
12
Issue
8
Pages
e0183757 - e0183757
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