Roadmap for investigating epigenome deregulation and environmental origins of cancer

Volume: 142, Issue: 5, Pages: 874 - 882
Published: Sep 13, 2017
Abstract
The interaction between the (epi)genetic makeup of an individual and his/her environmental exposure record (exposome) is accepted as a determinant factor for a significant proportion of human malignancies. Recent evidence has highlighted the key role of epigenetic mechanisms in mediating gene–environment interactions and translating exposures into tumorigenesis. There is also growing evidence that epigenetic changes may be risk factor-specific...
Paper Details
Title
Roadmap for investigating epigenome deregulation and environmental origins of cancer
Published Date
Sep 13, 2017
Volume
142
Issue
5
Pages
874 - 882
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