Adipokine genes and radiographic hand osteoarthritis in Finnish women: a cross-sectional study

Available evidence suggests that genetic factors and overweight play major roles in the aetiology of osteoarthritis (OA). We analysed the association of 18 single-nucleotide polymorphisms (SNPs) from nine adipokine and adipokine receptor genes (LEP, LEPR, ADIPOQ, RETN, NAMPT, SERPINA12, ITLN1, RARRES2, and APLN) with radiographic hand OA.The study design was cross-sectional. Bilateral hand radiographs of 542 occupationally active Finnish female...