Hippocampal sclerosis, hippocampal neuron loss patterns and TDP‐43 in the aged population
Abstract
Hippocampal neuron loss is a common neuropathological feature in old age with various underlying etiologies. Hippocampal sclerosis of aging (HS‐Aging) is neuropathologically characterized by severe CA1 neuronal loss and frequent presence of transactive response DNA‐binding protein of 43 kDa (TDP‐43) aggregations. Its etiology is unclear and currently no standardized approaches to measure HS‐Aging exist. We developed a semi‐quantitative protocol,...
Paper Details
Title
Hippocampal sclerosis, hippocampal neuron loss patterns and TDP‐43 in the aged population
Published Date
Sep 25, 2017
Journal
Volume
28
Issue
4
Pages
548 - 559
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